Applications of pharmacogeneticsWhat is pharmacogenetics? Pharmacogenetics studies the genes that regulate the activity, metabolism and transport of drugs, identifying the genetic polymorphisms involved in each process. The most frequent cause of therapeutic failure and adverse reactions is found in the variability of each patient’s response to drugs. The individual pharmacogenetic profile allows the use of…
Adapting the drug to your patient’s dose Know to prevent This genetic study allows to identify patients in whom a certain treatment will not be effective or may have a high risk of adverse effects. Application The study is indicated: In people with a different drug effect than expected In people with a family…
Clinical use This study helps to evaluate the possibility of reducing or increasing the response to analgesics metabolized by CYP2D6 and CYP2C19 enzymes. It can also be used as a treatment strategy guide for patients who are currently taking or are being considered for these medications. Clinical history Opioids are widely used for the management…
Pharmacogenetics is the genetic variability in the response to drugs. Pharmacogenetics aims to develop a more effective and safe therapy, reducing costs, and therefore improving the quality of care. The predictive value of pharmacogenetic analysis prevents the possible appearance of adverse effects, and allows a more personalized dose adjustment. Medications are currently one of the…
Para empezar a monitorear mi salud en espera de mi respuesta de nutrigenética, me realicé un estudio de sangre para ver mi estado general de salud. Los resultados para mi fueron en general buenos, pero si salió un poco bajo mi hemoglobina.
Results of mutations in the ALDOB gene that codes for the enzyme aldolase B, responsible for the metabolism of fructose (sugar commonly present in fruits and vegetables). It happens in many children. Sometimes the diagnosis is only made until adulthood when there is an aversion to the ingestion of sweets and fruits. Ingesting foods containing…
This disease is increasingly common in adults. It results from a decrease or absence of an enzyme needed to metabolize lactose (sugar found in milk and other milk products). If there is damage in the small intestine, it can produce less enzyme lactase, which causes intolerance to lactose. There may be damage to the small…
It is a multifactorial autoimmune disease manifested as gluten intolerance, involving both genetic and environmental factors. Celiac disease affects both adults and children Some genes have variants that confer an increased susceptibility to developing the disease. The most important related genes are HLA-DQA1 and HLA-DQB1. Other related genes are (IL21, IL18RAP, RGS1, SH2B3, MY098 and…
ADAPTING THE DRUG AND ITS DOSE TO THE PATIENT Pharmacogenetics in psychiatry There is a great variability in the way in which patients respond to drugs, in the appearance of side effects and in the symptoms caused by the toxicity of the drugs. The variation depends on factors such as age, sex, liver and kidney…
