At Genolife we perform human papillomavirus detection from cervical, urethral, buccal, liquid cytology and kerosene blocks. This test is performed by identifying the HPV DNA present in the biological sample. The technique used is the Polymerase Chain Reaction (PCR).
This test is recommended for sexually active women who want to protect themselves from potential oncogenic infections that can cause cervical cancer. You can request this test directly from the lab or through your trusted doctor.
A man infected with human papillomavirus (HPV) can infect his sexual partner even if he has no visible symptoms of the condition on his genitals. This test can be ordered directly from the laboratory.
There are currently several types of HPV tests, and it is important to know which ones have clinical utility. Tests that only detect the presence of HPV have no clinical relevance because they do not identify the risk; therefore, you do not know whether there is a danger or not. As we mentioned, 90% of sexually active people will at some point have some type of HPV—the important thing is to know which one. There are HPV tests that identify high-risk and low-risk types; these tests categorize the virus into two subtypes, indicating whether you have a high-risk or low-risk type without specifying the exact subtype. This test has moderate clinical utility.
At Genolife, we perform specific identification of 44 viral subtypes. This test is highly clinically useful because it allows your doctor to determine your specific risk with greater precision. Furthermore, if you have any symptoms, co-infections, and/or risk factors, your doctor will be able to provide personalized monitoring and treatment.
Genolife identifies 21 high-risk (HR) HPV subtypes: 16, 18, 26, 31, 33, 34, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68, 70, 73, 82, and 23 low-risk (LR) HPV subtypes: 6, 11, 13, 32, 40, 42, 43, 44, 54, 55, 57, 61, 62, 64, 69, 71, 72, 81, 83, 84, 87, 89, and 90.
High-Risk HPV (HR)
16, 18, 31, 33, 45, and 58
These viral subtypes are associated with the following pathologies: malignant mucosal lesions, squamous lesions, cervical intraepithelial neoplasia, cervical adenocarcinoma, malignant cervical neoplasms, squamous cell cancer, cervical adenocarcinoma and cervical cancer.
35, 39, 51, 52, 56, 59, 66, 68, and 70
26, 34, 53, 67, 73, and 82
These viral subtypes are related to the following pathologies: Malignant mucosal lesions.
Low Risk (BR) HPV
6, 11, 55, 64, and 69
These viral subtypes are associated with the following pathologies: recurrent respiratory papillomatosis, conjunctival papillomas/carcinomas, low-risk cervical intraepithelial neoplasia, verrucous carcinoma, benign mucosal lesions, genital warts in men and women, laryngeal papillomas.
13, 32, 40, and 43
These viral subtypes are associated with the following conditions: benign mucosal lesions and verrucous carcinoma.
42, 44, 54, 57, 61, 62, 71, 72, 81, 83, 84, 87, 89 y 90
These viral subtypes are related to the following pathologies: Low-risk lesions in the oral or genital mucous membranes.
Human papillomavirus, or HPV, is the most common virus affecting the male and female reproductive systems. Most of the sexually active women and men will become infected at some point in their lives, and some people may have recurrent infections. This virus is found in the mucous membranes.
Most men and women become infected soon after the onset of sexual activity. HPV is transmitted through sexual or skin-to-skin contact. Pregnant women can infect their newborns at birth only if natural childbirth in eyes, nose and/or throat.
There are many types of HPV and many of them do not cause problems. HPV infections usually clear up without any intervention within a few months after they are contracted, and around the 90% disappears after 2 years. However, a percentage of infections by some HPV viral subtypes can persist and become cancer.
Although most HPV infections can be of non-oncogenic viral subtypes and go away on their own, all individuals are at risk for infection with the viral subtypes High-risk oncogenic HPV (16, 18, 31, 33, 45, 52 and 58) and become complicated, progressing to precancerous lesions that may progress to invasive cancer.
Cervical cancer is the disease directly related to an infection with the viral subtypes of HPV known as “cervical cancer.“high-risk“. Infection with some types of HPV can also cause other types of cancer such as anal, vulvar, vaginal, penile, and oropharyngeal cancers, which are preventable with the detection of the infection.
The types of Non-oncogenic HPV (especially types 6 and 11) can cause genital warts and respiratory papillomatosis (a disease characterized by the appearance of tumors in the respiratory tract, extending from the nose and mouth to the lungs). Although this disease is rarely fatal, the number of very high relapse. Genital warts are very common and very contagious.