Intolerance to gluten (celiac disease)
It is a multifactorial autoimmune disease manifested as gluten intolerance, involving both genetic and environmental factors. Celiac disease affects both adults and children Some genes have variants that confer an increased susceptibility to developing the disease. The most important related genes are HLA-DQA1 and HLA-DQB1. Other related genes are (IL21, IL18RAP, RGS1, SH2B3, MY098 and…