Clinical use This study helps to evaluate the possibility of reducing or increasing the response to analgesics metabolized by CYP2D6 and CYP2C19 enzymes. It can also be used as a treatment strategy guide for patients who are currently taking or are being considered for these medications. Clinical history Opioids are widely used for the management…
Test for evaluation of treatment in breast cancer Breast cancer is the second cause of death in women of reproductive age in Mexico; tamo-xifen is the drug that is commonly prescribed to patients with this type of cancer, however the results of the therapy are often not as expected. Several studies have shown that endoxifene…
Pharmacogenetics is the genetic variability in the response to drugs. Pharmacogenetics aims to develop a more effective and safe therapy, reducing costs, and therefore improving the quality of care. The predictive value of pharmacogenetic analysis prevents the possible appearance of adverse effects, and allows a more personalized dose adjustment. Medications are currently one of the…
Para empezar a monitorear mi salud en espera de mi respuesta de nutrigenética, me realicé un estudio de sangre para ver mi estado general de salud. Los resultados para mi fueron en general buenos, pero si salió un poco bajo mi hemoglobina.
Results of mutations in the ALDOB gene that codes for the enzyme aldolase B, responsible for the metabolism of fructose (sugar commonly present in fruits and vegetables). It happens in many children. Sometimes the diagnosis is only made until adulthood when there is an aversion to the ingestion of sweets and fruits. Ingesting foods containing…
This disease is increasingly common in adults. It results from a decrease or absence of an enzyme needed to metabolize lactose (sugar found in milk and other milk products). If there is damage in the small intestine, it can produce less enzyme lactase, which causes intolerance to lactose. There may be damage to the small…
It is a multifactorial autoimmune disease manifested as gluten intolerance, involving both genetic and environmental factors. Celiac disease affects both adults and children Some genes have variants that confer an increased susceptibility to developing the disease. The most important related genes are HLA-DQA1 and HLA-DQB1. Other related genes are (IL21, IL18RAP, RGS1, SH2B3, MY098 and…
ADAPTING THE DRUG AND ITS DOSE TO THE PATIENT Pharmacogenetics in psychiatry There is a great variability in the way in which patients respond to drugs, in the appearance of side effects and in the symptoms caused by the toxicity of the drugs. The variation depends on factors such as age, sex, liver and kidney…
This is a chronic disease that occurs in two different forms: Crohns disease (or regional enteritis) and ulcerative colitis. The first symptoms usually occur before 30 years of age (between 12 and 24 years), but can affect people of any age. First-degree relatives of people with inflammatory bowel disease have a 10-fold increased risk of…
Gonorrhea is one of the most frequent Sexually Transmitted Infections (STIs). The cause is the bacterium Neisseria Gonorrhoeae, which can grow and multiply easily in moist and warm areas of the reproductive system, including the cervix (the opening of the womb), the uterus (womb) and the fallopian tubes (also called oviducts) in women, and in…
