Liquid biopsy of cancerWith a blood sample we can fight cancer We now know that tumors release into the bloodstream a large number of molecules specific to each tumor in most early and advanced stage cancers. The concept of “liquid biopsy” refers to the detection of molecules that come from tumors, through the analysis of…
BRAF is a gene that codes for a protein involved in epidermal growth factor receptor (EGFR) signaling that is important in cell proliferation, angiogenesis, cell migration, cell survival and cell adhesion. In normal cells, this signaling pathway is not activated unless the growth factor binds to the Epidermal Growth Factor receptor (EGFR). BRAF is activated…
Genetic variants affect the relationship between the risk of colorectal cancer and the use of Aspirin Members of the Colon Cancer Family Registry (CCFR) and Genetics and Epidemiology projects of the Colorectal Cancer Consortium (GECCO) collected genetic and other data from more than 8,600 cases of colorectal cancer and 8,500 controls enrolled through studies in…
How does cancer develop? As cancer develops from multiple genetic changes, it is very complex. Among the genetic changes are the genetic variations of specific genes (oncogenes), or deletion / duplications of genes, chromosomal changes of chromosomes, alterations in gene expression, aberrant methylations, etc. In addition, it is highly variable in genomic characteristics. All this…
This test is a Molecular Multiplex Analysis in which the following are reviewed: Protein markers (tumor markers). Analysis of circulating tumor cells (ctc). A transcriptomic profile (genetic expression) is made. Genetic profile search for point mutations, deletions / duplications and SNPs (single nucleotide polymorphisms). Epigenetic profile (methylation study). Pharmacogenetic analysis. Nutrigenetics The purpose of this…
Early detection, the prognosis of the disease and a comprehensive therapeutic guide are key to saving a patient with cancer. At Genolife we use a simple blood test that can help you and your doctor stay up to date on the changes that cause the cancer to spread, become resistant or return. When the cancer…
The prostate, as it grows, can progressively compress the urethra and, therefore, cause difficulty urinating. This happens because this compression prevents the flow of urine from the bladder to the urethra and to the outside. The possible consequences are retention of urine in the bladder or reflux of urine into the kidneys and a need…
Genolife researchers report on a new test based on methods of personalized medicine and genomic medicine for the diagnosis of prostate cancer. In Mexico, approximately 2 in 10 men develop prostate cancer and approximately 5,500 succumb to the disease each year. The diagnosis of prostate cancer can be made through the blood test for prostate-specific…
Applications of pharmacogeneticsWhat is pharmacogenetics? Pharmacogenetics studies the genes that regulate the activity, metabolism and transport of drugs, identifying the genetic polymorphisms involved in each process. The most frequent cause of therapeutic failure and adverse reactions is found in the variability of each patient’s response to drugs. The individual pharmacogenetic profile allows the use of…
Adapting the drug to your patient’s dose Know to prevent This genetic study allows to identify patients in whom a certain treatment will not be effective or may have a high risk of adverse effects. Application The study is indicated: In people with a different drug effect than expected In people with a family…
